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Brilliant blue G assisted internal limiting membrane peeling on pathological myopic macular holes with retinal detachment

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
Issue:
6
DOI:
10.3760/cma.j.issn.1005-1015.2010.06.04
Key Word:
视网膜穿孔/外科学;玻璃体切除术;着色剂/治疗应用;近视,退行性/并发症;Retinal perforations/surgery;Vitrectomy;Coloring agents/therapeutic use;Myopia,degenerative/complications

Abstract: Objective To evaluate the safety and efficacy of brilliant blue G (BBG) assisted internal limiting membrane (ILM) peeling on pathological myopic macular holes with retinal detachment. Methods This is a prospective and non-controlled study. Twenty-seven high myopia patients (27 eyes) with macular holes and retinal detachment were enrolled. Routine examination was performed, including the best corrected visual acuity (BCVA), intraocular pressure, slit lamp microscope with +90 D pre-set lens, A- or B-ultrasound, optical coherence tomography (OCT) and visual field. All patients received vitrectomy with BBG-assisted ILM peeling and C3F8 gas tamponade. The 5 follow-up visits were at the first day, the seventh day, the first month, the third month and the sixth month after surgery. The BCVA, intraocular pressure,visual field, macular hole and retinal reattachment were comparatively analyzed. Results The ILM of all patients were peeled completely by BBG staining. There were no major complications such as corneal edema,anterior chamber reaction, elevated intraocular pressure, visual field defects. At the first month after surgery, macular hole closed and retina reattached in 26 eyes (96.3%), the macular hole did not close and retina re-detached in one eye (25. 9%). At the sixth month after surgery, BCVA of 25 eyes (92. 6%)increased, two eyes (7.4 % ) didn't change, the difference was statistically significant (t = 6.08, P<0.05).Conclusions BBG can fully stain ILM without any side effects. Vitrectomy with BBG-assisted ILM peeling is a safe and effective treatment for pathological myopic macular holes with retinal detachment.

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