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A case-control observation on risk factors in central retinal vein occlusion
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
- Issue:
- 3
- DOI:
- 10.3760/j.issn:1005-1015.2007.03.002
- Key Word:
- 视网膜静脉闭塞/病因学;危险因素;全身性疾病
Abstract： 目的 观察视网膜中央静脉阻塞(CRVO)患者与主要的全身性疾病、眼局部疾病以及相关危险因素的关系.方法 病例对照研究.患者组:76例病程在3个月内、经荧光素眼底血管造影(FFA)检查确诊、未进行过药物治疗的CRVO患者;对照组:76例非CRVO患者,既往无眼底血管性疾病史,以年龄和性别与患者组一对一相匹配.患者组按年龄分为≤45岁(25例,占32.9%)和＞45岁(51例,占67.1%)两个亚组;按FFA检查结果分为非缺血型(40例,占52.6%)和缺血型(36例,占47.4%)两个亚组.检测血脂、血压和空腹血糖等.各组之间分别进行全身性和眼局部性疾病以及相关危险因素的统计学比较.结果 患者组高血压和高脂血症患病率明显高于对照组(P＜0.001,P=0.001),而心、脑血管疾病、开角型青光眼的发病率、以及吸烟和饮酒生活习性上差异无统计学意义(P＞0.05).年龄≤45岁组中,患者组各项指标与对照组差异无统计学意义(P＞0.05).缺血型CRVO组,除高血压和高脂血症外,糖尿病发病率明显高于对照组(P＜O.001,P=0.031,P=0.024).结论 高血压和高脂血症为CRVO发病的全身性因素.此外,糖尿病与缺血型CRVO发病也相关.及时诊断和治疗全身性疾患对于CRVO的防治具有重要指导意义.
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