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Clinical analysis of retinal vein occlusion caused by systemic lupus erythematosus
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
- Issue:
- 4
- DOI:
- 10.3760/j.issn:1005-1015.2003.04.003
- Key Word:
- 红斑狼疮,系统性;视网膜静脉闭塞
Abstract： 目的探讨系统性红斑狼疮(systemic lupus erythematosus,SLE)并发视网膜静脉阻塞的临床特点.方法对9例12只眼SLE并发视网膜静脉阻塞的患者进行视力、眼底检查及检测血抗核抗体(antinuclear antibody,ANA)、抗双链DNA(抗dsDNA)、补体3(C3)、补体4(C4)和血红细胞沉降率(ery-throcyte sedimentation rate,ESR).3例行荧光素眼底血管造影(fundus fluorescein angiography,FFA)检查,并对伴有眼部其他表现或全身病变的患者进行分析.结果视网膜中央静脉阻塞(central retinalvein occlusion,CRVO)6例8只眼,视网膜分支静脉阻塞(branch retinal vein occlusion,BRVO)3例4只眼;3例5只眼FFA显示早期出现视网膜静脉及毛细血管广泛荧光渗漏;6例单眼视网膜静脉阻塞的对侧眼有4只眼有棉绒斑、视网膜出血等SLE眼底改变;4例合并有眼部干燥性角结膜炎或溃疡性睑缘炎,8例患者伴随有全身症状;所有病例ANA、抗dsDNA阳性、血ESR大于50 mm/h,6例C3下降,5例C4下降.结论SLE是导致视网膜静脉阻塞的全身病变之一.SLE并发视网膜静脉阻塞的患者其视力及视网膜静脉和毛细血管屏障功能损害严重,病变与SLE活动程度相关,并可合并其他眼部或全身性病变.
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