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Study on risk factors and laser therapy for retinopathy of prematurity
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PERINATAL MEDICINE
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.1007-9408.2006.06.006
- Key Word:
- 视网膜病,早产儿;危险因素;激光凝固术
Abstract： 目的 探讨早产儿视网膜病(retinopathy of prematurity,ROP)激光治疗效果及该病发生的相关危险因素.方法 以35例因各种疾病住院治疗的早产儿为观察对象.对性别、胎龄、出生体重、Apgar评分、出生时及出生后缺氧、贫血、黄疸、感染、母亲年龄及孕期情况进行观察并进行头颅B超检查.用x2检验、Fisher确切概率法、t检验以及Logistic回归做统计分析,评价激光治疗的疗效,分析早产儿视网膜病发生的危险因素.结果 35例患病早产儿中有27例发生早产儿视网膜病,发生率77.1%.25例患儿接受激光治疗,并分别于术后7～14 d及3个月进行随访,治愈率分别为74.1%和92.6%.ROP组出生体重(1144.81±284.83)g,明显小于未发病组(8例)出生体重(1743.75±423.79)g,P＜0.01;ROP组胎龄(29.04±2.70)周,明显小于未发病组胎龄(32.50±1.85)周,P＜0.01.且出生体重越低,胎龄越小,ROP发生率越高,P＜0.01.经Fisher确切概率法检验显示出生后缺氧、贫血等因素在ROP发病组与未发病组差异有统计学意义(P＜0.05).结论 早产儿视网膜病在伴随各种疾病的早产儿中发生率较常见患病率高,其发病与缺氧、贫血、胎龄和出生体重有关.对患病早产儿进行激光治疗可获得较好的疗效,采取早监测、早发现、早治疗,则可获得较好的预后.
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