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The Relations hip Between Interleukin-8 And Premature Brith
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PERINATAL MEDICINE
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1007-9408.1999.04.003
- Key Word:
- 白细胞介素8;中性白细胞;宫颈粘液;分娩,早产
Abstract： 目的 通过测定宫颈粘液中白细胞介素8(IL-8)的浓度及中性粒细胞数,探讨早产与感染的关系.方法 用酶联免疫吸附(ELISA)法,对82例先兆早产孕妇(研究组)和104例正常孕妇(对照组)宫颈粘液中IL-8进行检测,IL-8≥450 μg/L为阳性;在400倍显微镜下对49例先兆早产孕妇及104例正常孕妇宫颈粘液中中性粒细胞数进行检测.结果 研究组孕妇宫颈粘液中,IL-8阳性率及中性粒细胞数明显高于对照组.结论 通过此研究提示早产与生殖道感染有一定的关系,测定宫颈粘液中IL-8的含量可望成为预知早产及早产管理的一个有效方法.
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