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The Change of Serotonin and 5-hydroxyindole Acetate of Venous Blood in Normal Pregnancy Women and in Women with Pregnancy Induced Hypertension
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PERINATAL MEDICINE
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1007-9408.1999.01.002
- Key Word:
- 妊娠高血压综合征;血清素;羟基吲哚乙酸
Abstract： 目的 探讨血浆中5-羟色胺(5-HT)和5-羟吲哚乙酸(5-HIAA)与妊高征发病的关系.方法 采用高效液相色谱-电化学检测法测定正常妊娠各期孕妇组及妊高征组血浆中5-HT和5-HIAA含量.结果 正常妊娠各期孕妇组血浆中5-HT含量无显著差异;妊高征组血浆中5-HT含量(70.44±28.69 μg/L)明显高于正常晚孕组(24.96±6.57 μg/L)(P＜0.01);妊高征组血浆中5-HIAA含量(4.11±2.30 μg/L)较正常晚孕组(7.87±1.75 μg/L)明显降低,P＜0.01.结论 孕妇血浆中5-HT含量变化可能与妊高征血管收缩的病理过程有关.
- [1]任东平,杨梦庚,罗亚宁,等.妊高征患者血浆及血小板中5-羟色胺含量的测定[J].1997,(1).
- [2]唐爱国,吴轰,高洁生.高效液相色谱-电化学检测法同时测定血浆中5-羟色胺和5-羟吲哚乙酸[J].1995,(6).
- [3]M A, Cruz,C, González,W H, Sepúlveda,etc.Effect of histamine on human placental chorionic veins: interaction with serotonin.[J].1991,42.
- [4]G. M.Filshie,P.Maynard,C.Hutter,etc.Urinary 5-hydroxyindole acetate concentration in pregnancy induced hypertension.[J].1992,304(6836).
- [5]C M, Middelkoop,G A, Dekker,A A, Kraayenbrink,etc.Platelet-poor plasma serotonin in normal and preeclamptic pregnancy.[J].1993,39.
- [6]吴其夏主编.体液因素和血液循环病理生理学[M].1991.