Abstract： Objective To observe the effects of different hemofiltration rewarming velocity on deep hypothermiainduced by seawater immersion in dogs with abdominal trauma and to provide a theoretical basis and practical treatment profile for the medical care of casualties with seawater immersion.Methods The animal model of abdominal trauma coupled with deep hypothermia (27.5 ± 0.5 ℃ ) induced by seawater immersion was established and the animals were randomly divided into the rapid hemofiltration rewarming group (n =8,rewarmed to 38.0 ± 0.5 ℃ at a rate of 3℃/h),the slow hemofiltration rewarming group ( n =8,rewarmed to 38.0 ±0.5 ℃ at a rate of 1.5 ℃/h) and the external rewarming group (n =5,rewarmed to 38.0 ± 0.5 ℃ ).In the rewarming process,serum potassium,blood coagulation and blood gas analysis were detected in all the animal groups.Furthermore,mortality rates were also observed.Results The rectification of the extrinsic coagulation disorder and acidosis for the rapid hemofiltration rewarming group( 1.53 ± 0.38,1.02± 0.25 ) was superior to that of the slow hemofiltration rewarming group (2.63 ± 0.13,1.91 ± 0.17 ) ( P ＜0.05 ),while the rectification of hypokalemia for the former [(2.90 ± 0.51 ) mmol/L,( 3.05 ± 0.45 ) mmol/L ]was inferior to that of the latter [( 3.42 ± 0.94) mmol/L,(4.20 ± 1.01 ) mmol/L ]( P ＜ 0.05 ).The mortality for the rapid hemofiltration rewarming group was 12.5％,while the mortalities for the slow hemofiltration rewarming group and the external rewarming group were 37.5％ and 100％ respectively.Conclusions For medical care of the cases with abdominal trauma coupled with deep hypothermia induced by seawater immersion,hemofiltration rewarming at a rate of 3℃/h might help to improve treatment effects and decrease mortality.