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Observation of the sedation and analgesia effects of fentanyl and midazolam on post-operation infants with congenital heart disease

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Author:
No author available
Journal Title:
CHINA CLINICAL PRACTICAL MEDICINE
Issue:
8
DOI:
No doi available
Key Word:
芬太尼;咪唑安定;镇静;镇痛;婴幼儿;Fentanyl;Midazolam;Sedation;Analgesia;Infant

Abstract: Objective To obese the sedation and analgesia effects and adverse flects of infusing Fentanyl and Midazolam on post-cardiac surgery in infants.Methods Forty patients with congenital heart disease used in two groups for sedation.The effects and adverse effects of the sedation and analgesia were observed on 2 h,8 h,24 h,48 h after surgery of each group.And Ramsay,Comfort value were assessed simultancously in each group.Results There were significant difference in Ramsay、Comfort value on 2 h,8 h,24 h(P<0.05),and no differentce on 48 h between the two groups.Only one case in analgesia group showed temporarily bradycardia and hypotension and recovered in several minutes.No nausea,vomiting and bleeding were observed in the two groups.Conclusion The sedation and analgesia of midazolam and Fentanyl can be used safely and effectively in infants on the early stage of post-cardiac surgery.

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