You Position: Home > Paper
Value of Emission-transmission Registration in FDG SPECT Images on Diagnosis of Primary and Recurrence of Cancer
( views:325, downloads:8 )
- Author:
- No author available
- Journal Title:
- JOURNAL OF MODERN CLINICAL MEDICAL BIOENGINEERING
- Issue:
- 6
- DOI:
- 10.3760/cma.j.issn.1674-1927.2002.06.007
- Key Word:
- 双探头符合线路;融合显像;癌;诊断;脱氧葡萄糖
Abstract： 目的初步评价FDG SPECT/CT符合线路同机图像融合在肿瘤诊断及复发监测中的应用价值.方法经临床确诊的恶性肿瘤及恶性肿瘤治疗后怀疑复发或残留的患者53例(治疗前诊断8例、治疗后疑复发45例).经SPECT/CT同机联合扫描行FDG显像检查,用二次迭代法加衰减校正进行影像重建,与同期CT或(和)MR检查相比较.结果在治疗前诊断组中,8例恶性肿瘤患者FDG显像均呈阳性,CT(MR)亦全部发现病灶,但不能对病灶进行有效定性;在治疗(手术、放疗、化疗)后疑复发的45例患者中FDG与CT(MR)的假阳性、假阴性、真阳性、真阴性分别为0,4,32,9和3,7,29,6;FDG灵敏度、特异性、阳性预测值、阴性预测值分别为8*89%、100%、100%、69.2%;而CT或(和)MR分别为80.6%、66.7%、90.6%、46.2%.同机融合由CT提供的详细解剖资料能准确定位恶性病灶.结论带有X线CT的符合线路的SPECT/CT同机融合FDG显像是一种新的有效的核医学显像方法,尤其是对治疗后残余或复发的肿瘤,较CT(MR)及其它功能性检查图像等更具有较特异的定性和准确性定位诊断价值,值得临床推广应用.
- [1]顾兆祥,蒋茂松.功能和解剖影像的融合[J].2002,(1).
- [2]Sandler MP,Delbeke D,Patton JA.Image fusion using an integrated, dual-head coincidence camera with X-ray tube-based attenuation maps.[J].2000,41(8).
- [3]M, Pai,C H, Park,J H, Suh,etc.Fluorine-18 fluorodeoxyglucose imaging using dual-head coincidence positron emission tomography without attenuation correction in patients with head and neck cancer.[J].1999,24.
- [4]K M, Greven,D W, Williams,J W, Keyes,etc.Positron emission tomography of patients with head and neck carcinoma before and after high dose irradiation.[J].1994,74(4).
- [5]Sandler MP,Delbeke D.The role of hybrid cameras in oncology.[J].2000,30(4).
- [6]R L, Wahl,L E, Quint,R L, Greenough,etc.Staging of mediastinal non-small cell lung cancer with FDG PET, CT, and fusion images: preliminary prospective evaluation.[J].1994,191.