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Clinical Study on Curing Hyaline Membrane Disease with Pulmonary Surfactant
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- Author:
- No author available
- Journal Title:
- JOURNAL OF MODERN CLINICAL MEDICAL BIOENG INEERING
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1674-1927.2001.04.005
- Key Word:
- 肺透明膜病;肺表面活性物质
Abstract： 目的分析肺表面活性物质治疗肺透明膜病(HMD)的疗效及临床价值.方法观察20例HMD患儿Exsurf治疗前后肺功能机械通气参数及肺泡充气程度的变化.结果用药前后PaO2、动脉-肺泡氧分压比值上升为44±15～93±44mmHg、0.11±0.05～0.22±0.04,PaO2、PaCO2、氧合指数、动脉-肺泡氧分压比值治疗前后比较差异均有非常显著性(p<0.01),用药后12h机械通气参数较治疗前明显下降(p<0.05～0.01),用药后12h胸片提示肺部病变明显改善.用药后肺炎,颅内出血并发症为70%和35%.结论 HMD 患儿Exsurf治疗后肺功能和肺泡充气程度明显改善.
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