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Placenta preparations in the treatment of vitiligo
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1673-4173.2009.03.009
- Key Word:
- 白癜风;胎盘;治疗;Vitiligo;Placenta preparations;Therapy
Abstract： Vitiligo is a common depigmentation disorder,and its treatment remains a challenge.Placenta preparations contain proteins/peptides with molecular weight greater than 3000 and sphingolipids,which can induce melanogenesis through p38 MAPK and promote proliferation and difierentiation of melanoblasts.It has been demonstrated that placenta preparations are a safe and effective treatment with few adverse reactions for vitiligo,especially for childhood vitiligo affecting the scalp.
- [1]许爱娥,尉晓冬.黑素生成素治疗30例白癜风[J].2001,(6).
- [2]许爱娥,尉晓冬,武家才,等.胎盘中提取的黑素生成素有效成分分析及动物实验[J].2003,(2).
- [3]Li Y,Xu A,Guan C,etc.Melagenine modulates proliferation and differentiation of melanoblasts.[J].2008,22(2).
- [4]PRAJNAMOY PAL,RABINDRA ROY,PIJUSH K. DATTA,etc.Hydroalcoholic Human Placental Extract: Skin Pigmenting Activity and Gross Chemical Composition[J].1995,34(1).
- [5]Saha Bidisha,Singh Suman Kumar,Sarkar Chinmoy,etc.Transcriptional activation of tyrosinase gene by human placental sphingolipid[J].2006,23(3-4).
- [6]许爱娥,尉晓冬.Topical Melagenine for Repigmentation in Twenty-Two Child Patients with Vitiligo on the Scalp[J].2004,(2).
- [7]Bhadra R,Sarkar C,Tobin DJ,etc.Activation of the Mitf promoter by lipid-stimulated activation of p38-stress signalling to CREB[J].2006,19(6).
- [8]Bhadra R,Saha B,Singh SK,etc.Human placental lipid induces melanogenesis by increasing the expression of tyrosinase and its related proteins in vitro[J].2005,18(1).
- [9]Mandal SK,Das M,Bera R,etc.A human placental extract: in vivo and in vitro assessments of its melanocyte growth and pigment-inducing activities.[J].2002,41(11).
- [10]Sarkar C,Singh SK,Mandal SK,etc.Human placental protein/peptides stimulate melanin synthesis by enhancing tyrosinase gene expression[J].2006,285(1/2).
- [11]Bera R,Singh SK,Sarkar C,etc.Human placental lipid induces melanogenesis through p38 MAPK in B16F10 mouse melanoma[J].2005,18(2).
- [12]Peguet Navarro J,Popa I,Sportouch M,etc.Gangliosides from human melanoma tumors impair dendritic cell differentiation from monocytes and induce their apoptosis.[J].2003,170(7).