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Malignant melanoma and cutaneous depigmentation
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1673-4173.2009.01.011
- Key Word:
- 黑色素瘤;色素减退;早期诊断;Melanoma;Hypopigmentation;Early diagnosis
Abstract： Many kinds of cutaneous hypopigmentation may appear in patients with malignant melanoma,with a relatively higher incidance compared with general population.The appearance of hypopigrnentation may predict a better prognosis of malignant melanoma.This depigmentation could be either a consequence of dualistic immune-mediated response against common antigens shared by normal melanocytes and malignant melanoma cells,or a kind of antineoplastic-like reaction.The sudden emergence of vitiligo-like hypopigmentation or halo nevi near or apart from preexisting melanocytic nevi or malignant melanoma,may benefit the early diagnosis of malignant melanoma and its metastasis.
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