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Doubts and strategies in the treatment of follicular lymphoma

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Author:
No author available
Journal Title:
Journal of Leukemia & Lymphoma
Issue:
6
DOI:
10.3760/cma.j.issn.1009-9921.2012.06.002
Key Word:
淋巴瘤;滤泡型;无症状疾病;复发;利妥昔单抗;干细胞移植;维持治疗;Lymphoma,follicular;,Asymptomtic diseases;Recurrence;Rituximab;Stem cell transplantation;maintenance treatment

Abstract: In the past 5 years,the treatment paradigm for patients with follicular lymphoma(FL) has undergone significant changes,with the development of effective new agents that are now being used in the upfront,maintenance,and relapsed/refractory settings.Although these new therapies have led to improvements in patient outcomes,numerous questions remain regarding their optimal use in the treatment of the disease.In this article,the questions related to the timing of therapy for asymptomatic patients,strategies for treating advanced and relapsed/refractory disease,the safety and efficacy of rituximab maintenance and the evolving role of transplantation in the era of novel agents were responded.The latest data from clinical trials of investigational agents that are showing promise in FL were also discussed.

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