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Advances in treatment of elderly patients with acute myeloid leukemia

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Author:
No author available
Journal Title:
JOURNAL OF LEUKEMIA & LYMPHOMA
Issue:
9
DOI:
10.3760/cma.j.issn.1009-9921.2010.09.021
Key Word:
急性髓系白血病;老年人;治疗;Acute myeloid leukemia;Aged;Therapy

Abstract: Acute myeloid leukemias (AML) in elderly patients showed less well response to therapy as well as relative poor prognosis, due to features of both host and disease biology in the elder. During the past decade, treatments for elderly AML have yielded some advances, including improvements in conventional chemotherapy, application of novel chemotherapeutic agents, immunotherapy approaches, and investigation of epigenetic drugs and targeted therapies, to which some subgroups in clinical trials have showed better response. These advances in current treatments of elderly AML will be reviewed.

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