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放射性视神经病变研究进展

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Author:: No author available

Journal Title:: CHINESE JOURNAL OF OCULAR FUNDUS DISEASES

Issue:: 2

DOI:: 10.3760/cma.j.issn.1005-1015.2011.02.033

Key Word:: 视神经病变/流行病学;视神经病变/病因学;视神经病变/诊断;视神经病变/治疗;放射疗法/副作用

Abstract：放射性视神经病变(RON)是因邻近视路的头颈部放射治疗(放疗)而引起的迟发性进行性视神经并发症.临床表现以突发的、无痛性单眼或双眼视力进行性下降为主要特征.视路接受的照射剂量及照射范围是发生RON的关键因素.增强的核磁共振成像(MRI检查以及电生理检测具有一定的辅助诊断意义;结合其临床表现、相应辅助检查及头颈部放疗史可作出诊断.虽然高压氧治疗能在发病早期一定程度上改善RON的视力损害,但目前仍然缺乏行之有效的治疗方法.因此,在制定头颈部放疗计划时应充分考虑视神经、视交叉是否在照射范围内,并注意控制照射剂量,以防止RON的发生.

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