You Position: Home > Paper
Thrombolysis infusion via microcatheter treating central retinal artery occlusion
( views:281, downloads:124 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
- Issue:
- 1
- DOI:
- 10.3760/j.issn:1005-1015.2005.01.006
- Key Word:
- 视网膜中央动脉闭塞/治疗;尿激酶型纤溶酶原激活物/投药和剂量;插管法
Abstract： 目的观察导管介入眼动脉灌注尿激酶(urokinase)与静脉滴注尿激酶治疗视网膜中央动脉阻塞(CRAO)的效果及对全身的影响.方法超选插管至眼动脉灌注尿激酶患者6例,静脉滴注尿激酶溶栓患者7例,经荧光素眼底血管造影(FFA)判断动脉再通情况,同时作血液生化检查观察其对全身的影响.结果溶栓治疗次日插管组6例患者中有5例完全再通,1例部分再通,完全再通率达83.33%,而静脉组的7例患者中有3例完全再通,2例部分再通,2例不通,完全再通率42.86%,相差显著.插管组给药后血液中凝血系统指标无明显改变,与静脉给药组相比差异有统计学意义.结论导管介入眼动脉灌注尿激酶溶栓治疗效果较好,对全身影响小.治疗后的视力提高与阻塞时间有关,提示发病后应及早进行治疗.
- [1]刘家琦.实用眼科学[M].1995.
- [2]S, Sherry,E, Gustafson.The current and future use of thrombolytic therapy.[J].1985,25.
- [3]马志中,李宝民,窦洪亮,等.经眼动脉超选插管溶栓治疗视网膜中央动脉阻塞[J].1996,(6).
- [4]M S, Korenfeld.Vasospasm and transient monocular blindness.[J].1992,326(12).
- [5]S S, Hayreh,H E, Kolder,T A, Weingeist.Central retinal artery occlusion and retinal tolerance time.[J].1980,87(1).
- [6]K H, Türmer,A, Guhl,H, Hettesheimer,etc.[Technique of selective, controlled retinal fibrinolysis in a model].[J].1993,90.
- [7]D. Schmidt,M. Schumacher,A.K. Wakhloo.Microcatheter Urokinase Infusion in Central Retinal Artery Occlusion[J].1992,113(4).
- [8]A K, Vine,M M, Samama.The role of abnormalities in the anticoagulant and fibrinolytic systems in retinal vascular occlusions.[J].1900,37(4).