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Progress on ferroptosis in pregnancy-related diseases

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Journal Title:
Chinese Journal of Perinatal Medicine
Key Word:
铁死亡;先兆子痫;糖尿病,妊娠;妊娠并发症;Ferroptosis;Pre-eclampsia;Diabetes, gestational;Pregnancy complications

Abstract´╝Ü Ferroptosis, a new form of programmed cell death, could be regulated by lipid metabolism, amino acid metabolism, and iron metabolism. Ferroptosis is closely related to human physiological mechanisms and involved in the development and progression of multiple diseases. More and more researchers have found that ferroptosis also plays a vital role in pregnancy-related disorders such as preeclampsia, gestational diabetes, and miscarriage. However, the mechanisms have not yet been fully understood. This article reviews the progress in ferroptosis in pregnancy-related diseases to provide new directions for scientific research and clinical treatment.

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