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Recent advances in simple plasma exchange therapy with regional citrate anticoagulation

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Author:: No author available

Journal Title:: Chinese Journal of Clinical Infectious Diseases

Issue:: 6

DOI:: 10.3760/cma.j.issn.1674-2397.2021.06.013

Key Word:: 血浆置换;单重血浆置换;局部枸橼酸抗凝;肝衰竭;Plasma exchange;Simple plasma exchange;Regional citrate anticoagulation;Liver failure

Abstract： Plasma exchange therapy is applied for treatment of severe immune diseases of multiple organ systems and severe liver diseases by removing pathogenic factors and regulating immune function. Regional citrate anticoagulation has no effect on systemic coagulation function and does not increase bleeding risk, and it is one of the optional anticoagulation methods for plasma exchange therapy. This article reviews recent literature on simple plasma exchange therapy with regional citrate anticoagulation to provide a reference for clinical application of this therapy.

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