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Application of glucocorticoids in treatment of COVID-19

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Author:
No author available
Journal Title:
Chinese Journal of Clinical Infectious Diseases
Issue:
1
DOI:
10.3760/cma.j.issn.1674-2397.2021.01.004
Key Word:
新型冠状病毒肺炎;糖皮质激素;细胞因子风暴;Coronavirus disease 2019;Glucocorticoid;Cytokine storm

Abstract´╝Ü The infection of 2019-nCoV can lead to overexpression of inflammatory factors, triggering cytokine storm and causing serious damage to the body. Glucocorticoids have anti-inflammatory properties and may be an effective treatment option. The use and dosage of glucocorticoids in coronavirus disease 2019 (COVID-19) remains controversial. This article reviews the theoretical basis, clinical evidence, debates and specific measures of glucocorticoids in the treatment of COVID-19, to provide reference for rational application of glucocorticoids in the future.

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