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Risk factors of secondary infection after transcatheter arterial chemoembolization for patients with liver cancer
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Clinical Infectious Diseases
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1674-2397.2020.04.007
- Key Word:
- 肝细胞癌;介入治疗;肝动脉化疗栓塞术;继发感染;高危因素;Hepatocellular carcinoma;Interventional therapy;Transcatheter arterial chemoembolization;Secondary infection;Risk factor
Abstract： 目的:研究肝癌患者介入术后感染的发生情况及高危因素。方法:回顾性分析浙江省人民医院2017年1月至2019年12月行肝动脉化疗栓塞术(TACE)的肝癌患者1 124例，根据是否发生术后感染，将其分为术后感染组(n＝96)和非感染组(n＝1 028)，采用多因素Logistic回归分析TACE术后发生感染的危险因素。结果:96例(8.5%)肝癌患者发生术后感染。Logistic回归分析发现，术前白蛋白水平( OR＝0.332，95.0% CI 0.208～0.532)是TACE术后感染的保护因素，肝癌破裂出血史( OR＝2.560，95.0% CI 1.503～4.362)和既往肝脓肿史( OR＝5.637，95.0% CI 3.133～10.143)是TACE术后感染的危险因素( P值均<0.01)。 结论:患者术前如白蛋白水平低、合并肝癌破裂出血史和既往肝脓肿史等高危因素，必须采取一定的预防措施，降低患者TACE的术后感染率。
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