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Clinical efficacy of probiotics supplementation on standard triple therapy for Helicobacter pylori eradication
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Clinical Infectious Diseases
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1674-2397.2012.02.011
- Key Word:
- 益生菌;幽门螺杆菌;根除率;Probiotics;Helicobacter pylori;Eradicationrate
Abstract： 幽门螺杆菌(Helicobacter pylori,HP)从发现至今已有20多年的历史,已被确认与慢性胃炎、消化性溃疡、胃黏膜相关淋巴样组织淋巴瘤和胃癌密切相关.根除HP可以减少37％人群胃癌的发生及阻止无癌前病变人群胃癌的发生[1].目前国内推荐的标准三联疗法HP根除率均在80％以下.如何避免和克服耐药,成功根除HP成为当前临床工作较为棘手的问题.微生态疗法为HP相关疾病的防治提供了新的思路.大量研究结果提示,益生菌对HP具有间接或直接的抑制作用[2].本研究的目的在于评价益生菌联合三联疗法7d或10 d疗法对HP根除的疗效.
- [1]吕农华,祝荫.幽门螺杆菌耐药的现状与对策[J].2011,(1).
- [2]赵保民,赵曙光,李慧艳,等.益生菌提高幽门螺杆菌根除率的临床研究[J].2010,(11).
- [3]卢春燕,张磊,许建明,等.以高剂量和标准剂量埃索美拉唑为基础的三联疗法根除幽门螺杆菌疗效比较[J].2010,(12).
- [4]王锦鸿,王江滨.幽门螺杆菌对胃黏膜的损伤机制及益生菌的保护作用[J].2007,(1).
- [5]刘东红.微生态制剂的进展与临床应用评价[J].2006,(3).
- [6]成虹,胡伏莲.第三次全国幽门螺杆菌共识会议[J].2007,(11).
- [7]Brzozowski T,Konturek PC,Mierzwa M,etc.Effect of probiotics and triple eradication therapy on the cyclooxygenase (COX)-2 expression, apoptosis, and functional gastric mucosal impairment in Helicobacter pylori-infected Mongolian gerbils[J].2006,11(1).
- [8]Kim HY,Parvez S,Kang SA,etc.Probiotics and their fermented food products are beneficial for health[J].2006,100(6).
- [9]Tian Zou,Jie Dong,Xiaofeng Yu.Meta-Analysis: Lactobacillus Containing Quadruple TherapyVersus Standard Triple First-Line Therapy for Helicobacter pyloriEradication[J].2009,14(5).