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Clinical efficacy of probiotics supplementation on standard triple therapy for Helicobacter pylori eradication

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Author:
No author available
Journal Title:
Chinese Journal of Clinical Infectious Diseases
Issue:
2
DOI:
10.3760/cma.j.issn.1674-2397.2012.02.011
Key Word:
益生菌;幽门螺杆菌;根除率;Probiotics;Helicobacter pylori;Eradicationrate

Abstract´╝Ü 幽门螺杆菌(Helicobacter pylori,HP)从发现至今已有20多年的历史,已被确认与慢性胃炎、消化性溃疡、胃黏膜相关淋巴样组织淋巴瘤和胃癌密切相关.根除HP可以减少37%人群胃癌的发生及阻止无癌前病变人群胃癌的发生[1].目前国内推荐的标准三联疗法HP根除率均在80%以下.如何避免和克服耐药,成功根除HP成为当前临床工作较为棘手的问题.微生态疗法为HP相关疾病的防治提供了新的思路.大量研究结果提示,益生菌对HP具有间接或直接的抑制作用[2].本研究的目的在于评价益生菌联合三联疗法7d或10 d疗法对HP根除的疗效.

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