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Successive treatment for patients with chronic hepatitis B who failed in "rescue therapy"

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF CLINICAL INFECTIOUS DISEASES
Issue:
4
DOI:
10.3760/cma.j.issn.1674-2397.2009.04.015
Key Word:
肝炎;乙型;慢性;拉米夫定耐药;阿德福韦酯;Chronic hepatitis B;Lamivudine resistance;Adefovir dipivoxil

Abstract´╝Ü @@ 在慢型乙型肝炎(CHB)抗病毒治疗过程中,当患者产生对拉米夫定(LAM)耐药,并同时出现肝炎再活动,首选的治疗方法是加用阿德福韦酯(ADV),通常肝炎活动可以再次得到控制,这种方法被称为"挽救性治疗"[1].然而,少数患者在接受挽救性治疗后疗效仍然不佳,给抗病毒治疗带来了巨大挑战.笔者对这部分患者的后续治疗进行了研究和分析.

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