Paper - WANFANG MED ONLINE

You Position: Home > Paper

Research progress of curcumin in the prevention and treatment of periodontitis

( views:0, downloads:0 )

Author:: No author available

Journal Title:: Chinese Journal of Stomatology

Issue:: 9

DOI:: 10.3760/cma.j.cn112144-20191118-00412

Key Word:: 姜黄素;牙周炎;抑菌作用;抗炎作用;研究进展;Curcumin;Periodontitis;Anti-bacterial Effect;Anti-inflammatory effect;Research progress

Abstract： Curcumin is a plant-derived polyphenol extracted from the rhizome of turmeric. As curcumin has such favorable properties as anti-inflammation, anti-oxidation, anti-angiogenesis, immune regulation, anti-bacterial and pro-apoptosis and showed few side effects, the application of curcumin in prevention and treatment of periodontal diseases is promising. This article reviewed the research progress of curcumin in the prevention and treatment of periodontitis.

Reference

[1]寇育荣,潘亚萍.牙龈卟啉单胞菌膜泡诱导牙龈上皮细胞炎性反应的体外研究[J].2007,(9).
[2]张辛燕,陈晓芳,孙正,等.乳香酸与姜黄素对二甲基苯并蒽诱导地鼠口腔癌的化学预防作用[J].2011,(11).
[3]Ricciotti E,FitzGerald GA.Prostaglandins and inflammation.[J].2011,31(5).
[4]Hugar, Shweta S.,Patil, Suvarna,Metgud, Renuka,etc.Influence of application of chlorhexidine gel and curcumin gel as an adjunct to scaling and root planing: A interventional study.[J].2016,(2).
[5]Sheetal Chauhan,Monika Bansal,Gayasuddin Khan,etc.Development, optimization and evaluation of curcumin loaded biodegradable crosslinked gelatin film for the effective treatment of periodontitis[J].2018,44(7).
[6]Chang-Jie,Xiao,Xi-Jiao,Yu,Jian-Li,Xie,etc.Protective effect and related mechanisms of curcumin in rat experimental periodontitis.[J].2018,14(1).
[7]Theodoro, Leticia Helena,Ferro-Alves, Marcio Luiz,Longo, Mariellen,etc.Curcumin photodynamic effect in the treatment of the induced periodontitis in rats[J].2017,32(8).
[8]Azizi, Arash,Shohrati, Parastoo,Goudarzi, Mehdi,etc.Comparison of the effect of photodynamic therapy with curcumin and methylene Blue on streptococcus mutans bacterial colonies[J].2019,27(Sep.).
[9]Cianciulli, Antonia,Calvello, Rosa,Porro, Chiara,etc.PI3k/Akt signalling pathway plays a crucial role in the anti-inflammatory effects of curcumin in LPS-activated microglia[J].2016,36.
[10]Supreet.Kaur,Richa.Sharma,Vandana.Sarangal,etc.Evaluation of anti-inflammatory effects of systemically administered curcumin, lycopene and piperine as an adjunct to scaling and root planing: A clinical study[J].2017,38(2).
[11]M, Nagasri,M, Madhulatha,S V V S, Musalaiah,etc.Efficacy of curcumin as an adjunct to scaling and root planning in chronic periodontitis patients: A clinical and microbiological study.[J].2015,7.
[12]Philip M. Preshaw.Host modulation therapy with anti‐inflammatory agents[J].2018,76(1).
[13]Qing, Pan,Qiang, Zhang,Jun, Chu,etc.Chlamydia abortus Pmp18.1 Induces IL-1β Secretion by TLR4 Activation through the MyD88, NF-κB, and Caspase-1 Signaling Pathways.[J].2017,7(Spec ).
[14]Shahzad, Muhammad,Millhouse, Emma,Culshaw, Shauna,etc.Selected dietary (poly)phenols inhibit periodontal pathogen growth and biofilm formation[J].2015,6(3).
[15]Diego,Fernández-Lázaro,Juan,Mielgo-Ayuso,Jesús,Seco Calvo,etc.Modulation of Exercise-Induced Muscle Damage, Inflammation, and Oxidative Markers by Curcumin Supplementation in a Physically Active Population: A Systematic Review.[J].2020,12(2).
[16]Kim HY,Jou I,Joe EH,etc.Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia.[J].2003,171(11).
[17]Sethi G,Shishodia S,Sandur SK,etc.Inflammation and cancer: how hot is the link?[J].2006,72(11).
[18]BHATIA, MADHU,SARVESH UROLAGIN, SHILPA,BABU PENTYALA, KISHORE,etc.Novel Therapeutic Approach for the Treatment of Periodontitis by Curcumin.[J].2014,8(12).
[19]Landstrom M.The TAK1-TRAF6 signalling pathway.[J].2010,42(5).
[20]Kong, Ryong,Kang, Ok-Hwa,Seo, Yun-Soo,etc.MAPKs and NF-B pathway inhibitory effect of bisdemethoxycurcumin on phorbol-12-myristate-13-acetate and A23187-induced inflammation in human mast cells[J].2018,17(1 Pt.A).
[21]Te Zhou,Dong Chen,Qing Li,etc.Curcumin inhibits inflammatory response and bone loss during experimental periodontitis in rats[J].2013,71(2).
[22]Dong C,Davis RJ,Flavell RA.MAP kinases in the immune response.[J].2002,20.
[23]Sandra Amor,Laura A. N. Peferoen,Daphne Y. S. Vogel,etc.Inflammation in neurodegenerative diseases – an update[J].2014,142(2).
[24]Nakagawa, Yasuaki,Mukai, Shogo,Yamada, Shigeru,etc.Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study[J].2014,19(6).
[25]Hwang Sue-Yun,Kim Ju-Young,Kim Kyoung-Woon,etc.IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways[J].2004,6(2).
[26]Lamprini, Karygianni,Ali, Al-Ahmad,Aikaterini, Argyropoulou,etc.Natural Antimicrobials and Oral Microorganisms: A Systematic Review on Herbal Interventions for the Eradication of Multispecies Oral Biofilms.[J].2015,6.
[27]B R, Anuradha,Yendluri Durga, Bai,Sambhana, Sailaja,etc.Evaluation of Anti-Inflammatory Effects of Curcumin Gel as an Adjunct to Scaling and Root Planing: A Clinical Study.[J].2015,7(7).
[28]Sugumari, Elavarasu,Thangakumaran, Suthanthiran,Arthiie, Thangavelu,etc.Evaluation of superoxide dismutase levels in local drug delivery system containing 0.2% curcumin strip as an adjunct to scaling and root planing in chronic periodontitis: A clinical and biochemical study.[J].2016.
[29]Brandao, Dayane de Almeida,Spolidorio, Luis Carlos,Johnson, Francis,etc.Dose-response assessment of chemically modified curcumin in experimental periodontitis[J].2019,90(5).
[30]Maryam,Pourhajibagher,Nasim,Chiniforush,Abbas,Monzavi,etc.Inhibitory Effects of Antimicrobial Photodynamic Therapy with Curcumin on Biofilm-Associated Gene Expression Profile of Aggregatibacter actinomycetemcomitans.[J].2018,15(3).
[31]Hofling JF,Pimenta LA,Zanin IC,etc.Photosensitization of in vitro biofilms by toluidine blue O combined with a light-emitting diode.[J].2006,114(1).
[32]Kepu V,Raghava,Kalyani P,Sistla,Sarita J,Narayan,etc.Efficacy of Curcumin as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients: A Randomized Controlled Clinical Trial.[J].2019,20(7).
[33]P. J. M. Oosterwaal,F. H. M. Mikx,H. H. Renggli.Clearance of a topically applied fluorescein gel from periodontal pockets[J].1990,17(9).
[34]DiDonato JA,Lin A,Nemoto S.Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase.[J].1998,18(12).
[35]Amalraj, Augustine,Varma, Karthik,Jacob, Joby,etc.A Novel Highly Bioavailable Curcumin Formulation Improves Symptoms and Diagnostic Indicators in Rheumatoid Arthritis Patients: A Randomized, Double-Blind, Placebo-Controlled, Two-Dose, Three-Arm, and Parallel-Group Study[J].2017,20(10).
[36]Pourhajibagher, Maryam,Kazemian, Hossein,Chiniforush, Nasim,etc.Exploring different photosensitizers to optimize elimination of planktonic and biofilm forms of Enterococcus faecalis from infected root canal during antimicrobial photodynamic therapy[J].2018,24(Dec.).
[37].Synergic phototoxic effect of visible light or Gallium-Arsenide laser in the presence of different photo-sensitizers on Porphyromonas gingivalis and Fusobacterium nucleatum[J].2015,12(4).
[38]Muhammad Zafarullah,Faramaze Dehnade,Wen Qing Li.Oncostatin M-Induced Matrix Metalloproteinase and Tissue Inhibitor of Metalloproteinase-3 Genes Expression in Chondrocytes Requires Janus Kinase/STAT Signaling Pathway[J].2001,166(5).
[39]Wu C,Wang X,Yuan D,etc.Demethoxycurcumin, a natural derivative of curcumin attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-kappaB signaling pathways in N9 microglia induced by lipopolysaccharide.[J].2010,10(3).
[40]Bocher, Sarah,Wenzler, Johannes-Simon,Falk, Wolfgang,etc.Comparison of different laser-based photochemical systems for periodontal treatment[J].2019,27(Sep.).
[41]Ricci Donato, H��rica Adad,Pratavieira, Sebasti?o,Grecco, Clovis,etc.Clinical Comparison of Two Photosensitizers for Oral Cavity Decontamination.[J].2017,35(2).
[42]Xia Yang,Jian-Ning Lv,Hui Li,etc.Curcumin reduces lung inflammation via Wnt/β-catenin signaling in mouse model of asthma[J].2017,54(4).
[43].The subgingival microbiome associated with periodontitis in type 2 diabetes mellitus[J].2020,14(2).
[44]Betül Kocaadam,Nevin Şanlier.Curcumin, an active component of turmeric (Curcuma longa), and its effects on health[J].2017,57(13).
[45]Leonard,WJ,rb.niams.nih.gov,O'Shea,JJ.Jaks and STATs: biological implications.[J].1998,16.
[46]Sanjeela.Guru,Shaila.Kothiwale,Nitin.Saroch,etc.Comparative evaluation of inhibitory effect of curcumin and doxycycline on matrix metalloproteinase-9 activity in chronic periodontitis[J].2017,28(5).
[47]Pimentel Suzana P.,Casati Marcio Z.,Ribeiro Fernanda V.,etc.Impact of natural curcumin on the progression of experimental periodontitis in diabetic rats[J].2020,55(1).
[48]Melissa J. Thiel,Caralee J. Schaefer,Mark E. Lesch,etc.Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: Potential proinflammatory mechanisms[J].2007,56(10).
[49]Jungil, Hong,Mousumi, Bose,Jihyeung, Ju,etc.Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.[J].2004,25.
[50]Sandra Amor,Fabiola Puentes,David Baker,etc.Inflammation in neurodegenerative diseases[J].2010,129(2).
[51]Guimar?es,M.R.,Leite,F.R.M.,Spolidorio,L.C.,etc.Curcumin abrogates LPS-induced proinflammatory cytokines in RAW 264.7 macrophages. Evidence for novel mechanisms involving SOCS-1, -3 and p38 MAPK[J].2013,58(10).
[52]Burcu Bakır,Zuhal Yetkin Ay,H. İbrahim Büyükbayram,etc.Effect of Curcumin on Systemic T Helper 17 Cell Response; Gingival Expressions of Interleukin‐17 and Retinoic Acid Receptor‐Related Orphan Receptor γt; and Alveolar Bone Loss in Experimental Periodontitis[J].2016,87(11).
[53]Felicity D, Herrington,Ruaidhrí J, Carmody,Carl S, Goodyear.Modulation of NF-κB Signaling as a Therapeutic Target in Autoimmunity.[J].2016.
[54]Kevin, Garala,Parth, Joshi,Malay, Shah,etc.Formulation and evaluation of periodontal in situ gel.[J].2013,3(1).
[55]Kang BY,Hwang SY,Im S,etc.Inhibition of interleukin-12 production in lipopolysaccharide-activated macrophages by curcumin.[J].1999,384(2).
[56]Shamsoulmolouk, Najafi,Mina, Khayamzadeh,Mojgan, Paknejad,etc.An In Vitro Comparison of Antimicrobial Effects of Curcumin-Based Photodynamic Therapy and Chlorhexidine, on Aggregatibacter actinomycetemcomitans.[J].2016.
[57]Yeonseok Chung,Xuexian Yang,Seon Hee Chang,etc.Expression and regulation of IL-22 in the IL-17-producing CD4+T lymphocytes[J].2006,(11).
[58]Ping Hu,Ping Huang,Min Wei Chen.Curcumin attenuates cyclooxygenase-2 expression via inhibition of the NF-κB pathway in lipopolysaccharide-stimulated human gingival fibroblasts.[J].2013,37(5).
[59]Kaminska B.MAPK signalling pathways as molecular targets for anti-inflammatory therapy - from molecular mechanisms to therapeutic benefits[J].2005,1754(1/2).
[60]Boyle, D. L.,Soma, K.,Hodge, J.,etc.The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis[J].2015,74(6).
[61]Ravi R,Goggins MG,Ottenhof NA,etc.Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.[J].2010,9(8).
[62].Effect of local application of curcumin and ornidazole gel in chronic periodontitis patients.[J].1900,7(4).