Effect of 2-methacryloyloxyethyl phosphorylcholine on the protein-repellent property of dental adhesive
- Author:
- No author available
- Journal Title:
- Chinese Journal of Stomatology
- Issue:
- 3
- DOI:
- 10.3760/cma.j.issn.1002-0098.2016.03.009
- Key Word:
- 牙本质粘结剂;磷酸钙类;细菌黏附;甲基丙烯酰氧乙基磷酸胆碱;Dentin-bonding agents;Calcium phosphates;Bacterial adhesion;2-methacryloyloxyethyl phosphorylcholine
Abstract： Objective To evaluate the effect of 2-methacryloyloxyethyl phosphorylcholine(MPC) and nanoparticles of amorphous calcium phosphate(NACP) on the protein-repellent property of dental adhesive.Methods MPC and NACP were incorporated into SBMP as the test group.Scotchbond Multi-Purpose(SBMP) was used as control group.Human dentin shear bond strengths were measured.Protein adsorption onto samples was determined by micro bicinchoninic acid(BCA) method.A dental plaque microcosm biofilm model with human saliva as inoculum was used to investigate biofilm viability.Results The dentin bond strength of modified group was (28.7±2.2) MPa,which was not significantly different from that of the SBMP control group.The amount of protein adsorption in the modified group and the SBMP control group were (0.21 ±0.02) μg/cm2 and (4.17±0.45) μg/cm2 respectively.Lactic acid production of biofilms in modified group and SBMP control were (7.71 ± 1.01) mmol/L and (19.18 ± 2.34) mmol/L repectively.Conclusions MPC-NACP based dental adhesive greatly reduce the protein adsorption and bacterial adhesion,without compromising dentin shear bond strength.This novel bonding agent may have wide application.
- [1]朱松.光固化复合树脂聚合反应对收缩应力影响的研究进展[J].2015,(8).
- [2]徐帅,张凌,李芳,等.三种老化方式对全酸蚀粘接系统牙本质粘接界面稳定性的影响[J].2014,(6).
- [3]岳林,邱丽慧,高学军.唾液及菌斑液中蛋白成分与龋易感性的关系[J].2002,(1).
- [4]丁宁,张祖太,何敏,等.几种常用口腔材料细菌粘附性能比较[J].2014,(5).
- [5]Ishihara K,Nomura H,Mihara T,etc.Why do phospholipid polymers reduce protein adsorption?[J].1998,39(2).
- [6]De Vizio W,McBain AJ,Sreenivasan PK,etc.Development and characterization of a simple perfused oral microcosm[J].2005,98(3).
- [7]Zhang,N.,Melo,M.A.S.,Bai,Y.,etc.Novel protein-repellent dental adhesive containing 2-methacryloyloxyethyl phosphorylcholine[J].2014,42(10).
- [8]Mary Anne S. Melo,Lei Cheng,Ke Zhang,etc.Novel dental adhesives containing nanoparticles of silver and amorphous calcium phosphate[J].2013,29(2).
- [9]Satoshi Imazato.Antibacterial properties of resin composites and dentin bonding systems[J].2003,19(6).
- [10]黄姣.获得性膜形成的研究进展[J].2004,(0S1).
- [11]Cheng L,Exterkate RA,Ten Cate JM,etc.Effect of galla chinensis on growth and metabolism of microcosm biofilms.[J].2011,45(2).
- [12]Jennifer L. Moreau,Hockin H.K. Xu,Laurence C. Chow,etc.Nanocomposite containing amorphous calcium phosphate nanoparticles for caries inhibition[J].2011,27(8).
- [13]Moro T,Kawaguchi H,Ishihara K,etc.Wear resistance of artificial hip joints with poly(2-methacryloyloxyethyl phosphorylcholine) grafted polyethylene: comparisons with the effect of polyethylene cross-linking and ceramic femoral heads.[J].2009,30(16).
- [14]Busscher HJ,Rinastiti M,Siswomihardjo W,etc.Biofilm formation on dental restorative and implant materials.[J].2010,89(7).
- [15]J. N. R. O'Donnell,G. E. Schumacher,J. M. Antonucci.Amorphous Calcium Phosphate Composites and Their Effect on Composite-Adhesive-Dentin Bonding[J].2009,23(7).
- [16]Drummond JL.Degradation, fatigue, and failure of resin dental composite materials.[J].2008,87(8).
- [17]Lewis, A. L..Phosphorylcholine-based polymers and their use in the prevention of biofouling[J].2000,18(3).
- [18]Andrew J, McBain.Chapter 4: In vitro biofilm models: an overview.[J].2009,69.