Abstract: Objective To analyze craniofacial growth three-dimensionally for adolescents with normal occlusion in Beijing.Methods One hundred and twenty-six adolescents with normal occlusion were selected according to the criteria.The sample was divided into four age groups (53 within 4 years,30 within 7 years,27 within 10 years and 16 within 13 years).Information of growth was collected.Three-dimensional cephalometric system based on cone-bean CT was established.Results From 4 to 13 years Co-A increased (14.55 ± 1.15) mm on average on the left and (13.66 ± 1.14) mm on the right,and Co-Gn increased (22.89±1.40) mm on the left and (22.82 ± 1.38) mm on the right; and U1-NA increased (2.20 ±0.44) mm on the left and (1.60 ±0.46) mm on the fight; and CoL-CoR and GoL-GoR increased (13.31 ±1.21) mm and (18.59 ± 1.40) mm,and N-Me increased (18.03 ± 1.32) mm.SN-PP and SN-MPL basically remained unchanged.Conclusions Adolescents with normal occlusion in Beijing grew obviously in three-dimensions and developed harmoniously.