You Position: Home > Paper

Evidence-based quality assessment of 10-year orthodontic clinical trials in 4 major dental journals

( views:364, downloads:116 )
Author:
No author available
Journal Title:
CHINESE JOURNAL OF STOMATOLOGY
Issue:
2
DOI:
10.3760/cma.j.issn.1002-0098.2010.02.011
Key Word:
临床试验;随机对照试验;质量评估;Clinical trials;Randomized controlled trials;Quality assessment

Abstract: Objective To assess the quality of orthodontic clinical trials published in 4 major dental journals in the past 10 years and establish the reference standard for orthodontic clinical trials and quality control of dental journals. Methods All the clinical trials published in Chinese Journal of Stomatology, West China Journal of Stomatology, Journal of Practice Stomatology and Chinese Journal of Orthodontics from 1999 to 2008 were searched. The demographic information of the papers was extracted and the quality of the clinical trials according to the consolidated standards of reporting trials (CONSORT) was assessed. Results Four hundrend and ninty-four clinical trials were retrieved, and 21.3% (105/494) of them were supported by grants. For the study design, only 26. 1% (129/494) were prospective studies, and 3.8% (19/494) were randomized clinical trials. It was hard to evaluate precisely due to the lack of information about the details of the study designs. For the randomized clinical trials, the lack of details for randomization, allocation concealment, blinding and intension to treat compromised the quality. Conclusions The general quality of clinical trials in orthodontics is poor. It needs to be improved both in the clinical study design and the paper writing.

WanfangData CO.,Ltd All Rights Reserved
About WanfangData | Contact US
Healthcare Department, Fuxing Road NO.15, Haidian District Beijing, 100038 P.R.China
Tel:+86-010-58882616 Fax:+86-010-58882615 Email:yiyao@wanfangdata.com.cn