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Association between the ratio of triglyceride to high-density lipoprotein and carotid plaques in Uygur patients with metabolic syndrome

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Author:: No author available

Journal Title:: Chinese Journal of Health Management

Issue:: 4

DOI:: 10.3760/cma.j.issn.1674-0815.2018.04.017

Key Word:: No keyword available

Abstract：代谢综合征(MetS)是一组以肥胖、高血压、循环三酰甘油(TG)升高、高密度脂蛋白胆固醇(HDL-C)降低以及空腹血糖升高为主的复杂代谢性疾病[1],是引起动脉粥样硬化(AS)及其所致心血管疾病发病率和死亡率增加的重要因素[2-3].新疆维吾尔族人群MetS和心血管疾病的患病率均远高于同地区其他民族[4-5],边远地区的部分患者因对疾病重视不足、交通不便而耽误诊治,寻找快速、便捷、经济的指标筛检AS具有重要价值.尽管通过超声检查颈动脉斑块最为直接简便,但对于新疆来说,由于超声设备的较大差别和超声检查的主观性特点,该方法往往不能完全反映真实状况.TG/HDL-C比值是反映胰岛素抵抗的重要指标,与心血管疾病发病风险和死亡率显著相关[6].然而,TG/HDL-C比值预测胰岛素抵抗存在明显的民族差异性[7-8],它是否能够用于筛检维吾尔族MetS患者AS尚不清楚.因此,本研究以新疆维吾尔族MetS患者为研究对象,探讨TG/HDL-C比值与颈动脉斑块的关系,试图确定该比值的预测切点值.

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