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Clinical use of low-dose computed tomography chest screening combined with quantitative computed tomography in the screening of osteoporosis in adults

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Author:
No author available
Journal Title:
Chinese Journal of Health Management
Issue:
3
DOI:
10.3760/cma.j.issn.1674-0815.2018.03.015
Key Word:
No keyword available

Abstract´╝Ü 随着人口平均寿命的增长和老龄人口的增多,骨质疏松症已经成为全球性的公共健康问题.脊柱骨折作为其常见的并发症,严重影响患者的生活质量.如何早期诊断骨质疏松是预防和治疗骨质疏松性骨折的关键.骨密度降低是骨量减少的具体表现,检查骨密度是诊断骨质疏松症的重要手段.定量CT(quantitative computed tomography,QCT)测量的是椎体松质骨的体积骨密度(volum bone mineral density,vBMD),避免了邻近组织的影响,能够反映真正的骨密度.QCT诊断骨质疏松较传统的双能X线骨密度(dual energy X-ray absorptiometry,DXA)方法具有更高的敏感性和准确性[1].胸部低剂量CT检查对肺癌的早期检出、早期治疗、降低死亡率有极大的帮助[2],同时也用于肺部非肿瘤性病变,如气胸、肺炎、肺气肿、外伤等诊断和疗效评估.随着公众健康意识的增强和影像技术的提高,越来越多的人选择胸部低剂量CT进行体检筛查.本研究应用胸部低剂量CT联合脊柱QCT检查,探讨QCT在体检人群进行骨密度测量和骨质疏松筛查的可行性.

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