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慢性阻塞性肺疾病急性加重期并发肺动脉高压的高危血液生物标志物研究

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Author:: No author available

Journal Title:: Chinese Journal of Tuberculosis and Respiratory Diseases

Issue:: 8

DOI:: 10.3760/cma.j.cn112147-20200807-00881

Key Word:: No keyword available

Abstract：回顾性观察郑州大学第一附属医院2018年1月至2019年1月收治的慢阻肺急性加重患者302例，其中65例并发肺动脉高压，比较其临床特点，发现多项血液生物标志物在慢阻肺急性加重合并发肺动脉高压的患者中差异有统计学意义。进一步采用受试者工作特征曲线分析氨基末端脑钠肽前体（NT-proBNP）预测慢阻肺急性加重并发肺动脉高压的曲线下面积最大。相关血清生物标志物特别是NT-proBNP可能提示临床慢阻肺急性加重患者并发肺动脉高压，有一定的筛查价值。

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