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异基因造血干细胞移植术后肺部移植物抗宿主病的临床特点及细胞免疫特征
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Tuberculosis and Respiratory Diseases
- Issue:
- 12
- DOI:
- 10.3760/cma.j.issn.1001-0939.2019.12.015
- Key Word:
- No keyword available
Abstract： 对2017年1月至2019年4月本院收治的确诊为肺部移植物抗宿主病(GVHD)患者的肺功能、影像学及细胞免疫特征进行回顾性分析.肺部GVHD患者肺功能以混合性通气功能障碍为主,且多数伴有弥散功能障碍;胸部CT主要表现为支气管扩张及支气管壁增厚;肺部GVHD患者体内的CD4+淋巴细胞较无慢性GVHD患者明显活跃,淋巴细胞亚群结果对于判断移植后患者的免疫状态具有重要意义.
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