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大气细颗粒物对慢性阻塞性肺疾病病情影响的研究进展

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Author:: No author available

Journal Title:: Chinese Journal of Tuberculosis and Respiratory Diseases

Issue:: 3

DOI:: 10.3760/cma.j.issn.1001-0939.2018.03.015

Key Word:: No keyword available

Abstract：大气颗粒物是指悬浮在空气中的固体或液体颗粒的混合物,可分为粗颗粒物(PM10)和细颗粒物(PM2.5)以及超细颗粒物(PM0.1).粗颗粒物主要停留在鼻腔和呼吸道内的黏液里,可以通过正常呼吸活动轻松消除,而PM2.5及PM0.1可到达远端气道并沉积在肺泡区,导致呼吸道肺部疾病[1].慢性阻塞性肺疾病(慢阻肺)是一种可以预防和治疗的常见疾病,以持续性呼吸道症状和气流受限为特征,由暴露于有害颗粒物或气体造成气道和(或)肺泡异常所引起.慢阻肺已成为全球第三大死亡原因,正常人短期或长期暴露于PM2.5可引起一系列呼吸道症状,如咳嗽、喘息和呼吸困难等[2-3].

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