Clinical analysis of Beh(c)et disease associated with pulmonary vascular disease
- Author:
- No author available
- Journal Title:
- Chinese Journal of Tuberculosis and Respiratory Diseases
- Issue:
- 5
- DOI:
- 10.3760/cma.j.issn.1001-0939.2017.05.006
- Key Word:
- 白塞病;高血压,肺性;肺栓塞;肺动脉瘤;Behcet's disease;Hypertension,pulmonary;Pulmonary embolism;Pulmonary artery aneurysm
Abstract： Objective To investigate the clinical features,therapy and prognosis of Behcet's disease(BD) complicated with pulmonary vascular diseases (PVD).Methods The clinical manifestation,hemodynamics,pulmonary artery angiographic findings,therapy and prognosis of PVD in BD in Shanghai Pulmonary Hospital from January 2009 to August 2016 were analyzed retrospectively.Results Seven patients with average of (37 ± 20) years were included.The ratio of male vs.female was 6 ∶ 1.Vascular involvement included pulmonary hypertension (PH) (4/7),pulmonary embolism (PE) (3/7) and pulmonary artery aneurysms (PAA) (3/7).All patients received immunosuppressive agents and all PH patients had therapy of PH target drugs.Three out of 4 PE patients underwent anticoagulant therapy.Conclusion PVD is a rare complication of BD.The common clinical manifestations are PH,PE and PAA.Management of immunosuppressive agents may improve the prognosis and should be recommended.
- [1]魏华,茹晋丽,何俊梅,等.白塞病合并肺动脉高压八例临床分析并文献复习[J].2008,(10).
- [2]高金明,金宇虹,蔡柏蔷,等.白塞氏病合并肺动脉瘤附七例临床分析[J].2005,(5).
- [3]张亚男,赵宗兴,唐文芳,等.白塞病合并肺栓塞1例诊断分析[J].2014,(5).
- [4]荆志成,徐希奇,蒋鑫,等.经前臂静脉径路行右心导管检查和肺动脉造影的可行性研究[J].2009,(2).
- [5]中华医学会风湿病学分会.白塞病诊断和治疗指南[J].2011,(5).
- [6]刘永太,田庄,方理刚,等.白塞病血管受累的临床分析（附53例报告）[J].2007,(8).
- [7]彭劲民,张卓莉,董怡.白塞病173例的临床特点分析[J].2006,(3).
- [8]李忱,李菁,李梦涛.白塞病合并双肺动脉瘤及多发深静脉血栓1例[J].2013,(1).
- [9]A, Hamzaoui,K, Hamzaoui.[Pulmonary complications of Behcet's disease and Takayasu's arteritis].[J].2005,22(6 Pt 1).
- [10]Pierre Durieux,Oliver Bletry,Gérard Huchon,etc.Multiple pulmonary arterial aneurysms in Behcet's disease and Hughes-Stovin syndrome[J].1981,71(4).
- [11]G J, Burkill,P R, Burn,S P, Padley.Aneurysm of the left brachiocephalic vein: an unusual cause of mediastinal widening.[J].1997,70(836).
- [12]Oguz, Uzun,Tekin, Akpolat,Levent, Erkan.Pulmonary vasculitis in behcet disease: a cumulative analysis.[J].2005,127(6).
- [13]International Study Group for Behçet's Disease.Criteria for diagnosis of Behcet's disease[J].1990,335(8697).
- [14]Naim, Ceylan,Selen, Bayraktaroglu,Sukru Mehmet, Erturk,etc.Pulmonary and vascular manifestations of Behcet disease: imaging findings.[J].2010,194(2).
- [15]H Yazici,Y Tüzün,H Pazarli,etc.Influence of age of onset and patient's sex on the prevalence and severity of manifestations of Beh?et's syndrome.[J].1984,43(6).
- [16]Vedat Hamuryudan,Tarik Er,Emire Seyahi,etc.Pulmonary artery aneurysms in Behçet syndrome[J].2004,117(11).
- [17]Harman M,Arslan H,Ayakta H,etc.Fibrosing mediastinitis and thrombosis of superior vena cava associated with Behcet's disease.[J].2003,48(2).
- [18]Celenk C,Celenk P,Akan H,etc.Pulmonary artery aneurysms due to Beh\u00e7et's disease: MR imaging and digital subtraction angiography findings.[J].1999.
- [19]MehmetA.KuzuM.D.,CihangirÖzaslanM.D.,CüneytKöksoyM.D.,etc.Vascular involvement in Behçet's isease: 8-Year audit[J].1994,18(6).
- [20]Petty T. L..Recurrent pneumonia in Behcet's syndrome. Roentgenographic documentation during 13 years[J].1977.
- [21]Edrees, Amr,Naguib, Sherif,El Menyawi, Manal,etc.Pulmonary manifestations in a group of patients with Behcet's disease[J].2017,20(2).
- [22]Sarica Kucukoglu R,Yazganoglu KD,Erzengin D,etc.Vascular involvement in Behcet's disease: a retrospective analysis of 2319 cases.[J].2006,45(8).
- [23]Jiang, Rong,Ai, Zi-Sheng,Jiang, Xin,etc.Intravenous fasudil improves in-hospital mortality of patients with right heart failure in severe pulmonary hypertension[J].2015,38(8).
- [24]Hoeper, Marius,Lancellotti, Patrizio,Lang, Irene,etc.2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS) Endorse[J].2016,(1).
- [25]Tuzun H,Yurdakul S,Akman C,etc.Pulmonary artery involvement and associated lung disease in Behcet disease: a series of 47 patients.[J].2012,91(1).