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女性非小细胞肺癌纵览
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Tuberculosis and Respiratory Diseases
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1001-0939.2012.02.004
- Key Word:
- No keyword available
Abstract： 肺癌作为全球范围发病率和病死率最高的恶性肿瘤一直备受关注.近十年来,随着戒烟和生活习惯的改变,男性肺癌的发病率逐渐达到平台,甚至开始出现下降趋势,但女性肺癌的发病率出现快速上升,其发病高峰预计出现在2020年,这种增长趋势被称为一个"时代的流行",因而女性肺癌也逐渐得到重视.1.女性肺癌"流行"的原因:吸烟是肺癌的首要致病因素,全球范围内80％以上的男性及45％的女性肺癌与吸烟有关.由于历史性吸烟模式的影响,男性吸烟流行高峰较女性约早20年,这可以解释女性肺癌的流行高峰晚于男性,且发病率尚未开始下降的现状.此外,"女性对烟草致癌更敏感"的观点亦是解释女性肺癌快速增长的原因之一.但也有文献报道无论是曾经吸烟还是仍在吸烟,女性与男性肺癌的发病风险并没有差异[1-2].
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