You Position: Home > Paper
乌司他丁对百草枯中毒致急性肺损伤大鼠炎症因子的影响
( views:29, downloads:320 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1001-0939.2011.02.021
- Key Word:
- No keyword available
Abstract： @@ 百草枯是一种广泛应用的非选择性触杀型除草剂,对人畜有较强毒性,中毒后可累及多个重要器官,肺脏为主要靶器官,大剂量口服后可于24 h内迅速发生急性肺损伤(acute lung injury,ALI),1～3 d内出现ARDS[1],随后发生多器官功能衰竭,病死率高达80%.
- [1]磨静佳,赵晓琴,邝晓聪.百草枯致急性肺损伤大鼠模型的建立[J].2009,(2).
- [2]高燕,雍政,黄英,等.百草枯建立肺纤维化动物模型的实验研究[J].2003,(4).
- [3]李文放,陈杰.乌司他丁在急性呼吸窘迫综合征的临床应用研究[J].2006,(9).
- [4]赵晓琴,吴英林,邝晓聪.乌司他丁对大鼠急性肺损伤保护作用的实验研究[J].2008,(6).
- [5]Ando Y,Yamashita M,Yamashita M.A long-term follow-up of lung function in survivors of paraquat poisoning.[J].2000,19(2).
- [6]Tomita M,Ishikawa T,Adachi J,etc.Early differential gene expression of rat lung after exposure to paraquat.[J].2004,38(8).
- [7]Nys M,Preiser JC,Mathy Hartert M,etc.Nitric oxide-related products and myeloperoxidase in bronchoalveolar lavage fluids from patients with ALI activate NF-kappa B in alveolar cells and monocytes.[J].2005,43(6).
- [8]Homaidan FR,Chakroun I,El-Sabban ME,etc.The role of NF-kappaB in mediating the anti-inflammatory effects of IL-10 in intestinal epithelial cells.[J].2006,36(1).
- [9]Iwasaka H,Noguchi T,Ito K,etc.Effect of Ulinastatin, a human urinary trypsin inhibitor, on the oleic acid-induced acute lung injury in rats via the inhibition of activated leukocytes.[J].2005,36(3).
- [10]Victor VM,Rocha M,Esplugues JV,etc.Role of free radicals in sepsis: antioxidant therapy.[J].2005,11(24).
- [11]Buckley NA,Wilks MF,Eddleston M.Prospects for treatment of paraquat-induced lung fibrosis with immunosuppressive drugs and the need for better prediction of outcome: a systematic review.[J].2003,96(11).
- [12]Hwang KY,Lee EY,Hong SY.Paraquat intoxication in Korea.[J].2002,57(2).
- [13]D F, Fiorentino,A, Zlotnik,T R, Mosmann,etc.IL-10 inhibits cytokine production by activated macrophages.[J].1991,147.