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Radio-pathological manifestations of pulmonary sarcoidosis
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 8
- DOI:
- 10.3760/j.issn:1001-0939.2007.08.001
- Key Word:
- 结节病;病理学;体层摄影术,X线计算机
Abstract： 目的 探讨肺结节病的病理和影像学特征,提高临床诊断水平.方法 回顾性分析2000年1月至2005年8月在北京协和医院住院的46例肺结节病患者的病理和影像学资料.结果 46例肺内结节病患者支气管肺泡灌洗液中淋巴细胞为0.47±0.18,CD4/CD8为6.63±4.51,血清血管紧张素转化酶(ACE)水平为(47±16)U/L.12例胸部CT表现为纵隔肺门淋巴结对称性肿大.16例表现为肺内结节影,沿支气管纹理分布或散在随机分布,呈粟粒状.多发斑片状(实变影)为13例.双肺磨玻璃样变为5例;13例经开胸、胸腔镜和纵隔镜取病理,33例行经皮肺活检、经支气管镜黏膜或肺活检.镜下可见病变内无干酪坏死上皮样结节.结节间可见无细胞成分的玻璃样变物质.结节围绕血管、淋巴管及支气管黏膜下分布,部分病例可见肉芽肿性血管炎.结论 肺结节病胸部CT表现多样,确诊需要临床、支气管肺泡灌洗液检测结果和病理学表现并结合糖皮质激素疗效综合判断.
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