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北京汉族支气管哮喘患者白三烯C4合成酶A-444C基因多态性研究
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 11
- DOI:
- 10.3760/j:issn:1001-0939.2006.11.014
- Key Word:
- No keyword available
Abstract： @@ 白三烯C4合成酶(LTC4S)是生成硫肽白三烯(CysLT)的关键酶.目前国外部分研究发现LTC4S A-444C基因多态性与支气管哮喘(简称哮喘)患者肺功能下降、病情严重程度及应用白三烯受体拮抗剂的临床反应相关[1-3].我们的研究初步探讨了在北京无亲缘关系汉族哮喘患者中,LTC4S A-444C基因多态性与哮喘的关系.
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