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囊性纤维化跨膜传导调节体氯通道在离体大鼠肺泡液体清除中的作用
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 1
- DOI:
- 10.3760/j:issn:1001-0939.2006.01.017
- Key Word:
- No keyword available
Abstract： @@ 肺泡液体的清除能力和肺水肿之间存在着密切关系,肺泡液体清除率(alveolar fluid clearance,AFC)的提高可加快肺水肿液的清除.研究提示,活性钠离子的主动运输在肺泡液体清除过程中的作用非常重要[1,2];但是氯离子通道在肺泡液体清除过程中的作用尚不甚清楚.囊性纤维化跨膜传导调节体(cystic fibrosis transmembrance conductance regulator,CFTR)氯离子通道是存在于肺泡上皮中起最主要作用的一种氯离子通道,我们的实验就是探讨CFTR氯离子通道在液体清除中的作用.
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