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支气管哮喘患者痰中环氧合酶2表达及其临床意义
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 8
- DOI:
- 10.3760/j:issn:1001-0939.2005.08.017
- Key Word:
- No keyword available
Abstract： @@ 支气管哮喘(简称哮喘)是多种炎症细胞及其组分参与的复杂的病理过程,其中前列腺素和血栓素都是气道生理重要的调节物质,这些介质的形成需要环氧合酶(COX),我们的研究通过观察哮喘患者不同时期、不同控制情况下痰中环氧合酶2(COX-2)蛋白表达和COX-2代谢产物前列腺素E2(PGE2)浓度变化,探讨COX-2与哮喘气道炎症和病情的相关性,痰中PGE2测定是否可以作为反映哮喘气道炎症和病情变化的指标.
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