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Clinical analysis of diffuse panbronchiolitis in 9 cases with literature review
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 8
- DOI:
- 10.3760/j:issn:1001-0939.2005.08.004
- Key Word:
- 细支气管炎;活组织检查;诊断;鉴别
Abstract： 目的探讨我国弥漫性泛细支气管炎(DPB)的临床特点及诊断方法.方法将经开胸或胸腔镜肺活检证实的9例DPB患者的临床特点与日本修订的临床诊断标准进行比较分析.结果本组9例中8例有持续性咳嗽、咳痰及劳力性呼吸困难,7例有慢性鼻窦炎,7例肺部可闻及湿啰音,1例肺部可闻及哮鸣音;所有患者胸部CT均可见小叶中心性结节影,4例第一秒用力呼气容积/用力肺活量比值＜70%,5例动脉血氧分压(PaO2)＜80 mm Hg(1 mm Hg=0.133 kPa),1例冷凝集素滴度≥1∶ 64.4例符合临床确诊标准,3例符合一般诊断,2例不符.其中8例接受了经支气管镜肺活检,均未获得明确的病理诊断.结论多数根据临床诊断标准拟诊本病的患者可给予大环内酯类药物治疗.本病误诊率高的根本原因是对本病的临床特点、诊断标准不熟悉.经支气管镜肺活检对本病的诊断帮助不大,临床诊断困难者可行开胸或胸腔镜下肺活检.
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