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转化生长因子β1对人胚肺成纤维细胞平滑肌肌动蛋白α表达的影响
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 7
- DOI:
- 10.3760/j:issn:1001-0939.2004.07.013
- Key Word:
- No keyword available
Abstract： @@ 在肺纤维化动物模型以及人类特发性肺纤维化(IPF)中,纤维化肺组织局部不仅转化生长因子β1(TGF-β1)水平升高,而且还聚集了大量表达平滑肌肌动蛋白α(α-SMA)的肌成纤维细胞.肌成纤维细胞与肺纤维化进展过程密切.本研究拟探讨外源性TGF-β1对人胚肺成纤维细胞α-SMA蛋白和mRNA表达水平的影响.
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