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The macrophage receptors for uptaking Mycobacterium tuberculosis
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 5
- DOI:
- 10.3760/j:issn:1001-0939.2003.05.030
- Key Word:
- No keyword available
Abstract： @@ 结核分支杆菌是典型的胞内致病菌,它在机体内的主要宿主细胞是巨噬细胞[1].结核分支杆菌与巨噬细胞膜表面受体结合后,经膜内陷形成吞噬小体进入细胞,除了被细胞消化清除外,它有一系列的措施,如抑制巨噬细胞的激活,消除氧化基团,抑制细胞溶酶体与吞噬体的融合并抵抗溶酶体酶的作用,从而在细胞内存活下来.文中综述了与巨噬细胞摄取结核分支杆菌相关的受体,以及结核分支杆菌利用膜受体进入巨噬细胞的机制.
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