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脂质体前列腺素E1对急性肺损伤犬血流动力学和氧代谢的影响
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 12
- DOI:
- 10.3760/j:issn:1001-0939.2002.12.018
- Key Word:
- No keyword available
Abstract： @@ 脂质体前列腺素E1(lip-PGE1)用含肺磷脂的脂质体作为药物载体,能够增加PGE1扩张血管、抑制血小板聚集和改善炎症的作用[1].实验表明,无脂质体PGE1可以提高急性呼吸窘迫综合征(ARDS)患者的心输出量,但不能改善氧合[2-3].但lip-PGE1是否改善急性肺损伤时心输出量和氧合指标的报道尚少,我们的实验将观察lip-PGE1对油酸型急性肺损伤(OA-ALI)犬血流动力学和氧代谢的影响.
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