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hsp70/CD80嵌合DNA真核表达质粒的构建及鉴定
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF TUBERCULOSIS AND RESPIRATORY DISEASES
- Issue:
- 4
- DOI:
- 10.3760/j:issn:1001-0939.2002.04.017
- Key Word:
- No keyword available
Abstract： @@ 我们将结核分支杆菌hsp70和人CD80的编码基因进行连接重组,构建成hsp70/CD80嵌合DNA真核表达质粒,为进一步研究其免疫保护效果及制备结核病hsp70/CD80嵌合DNA疫苗奠定了基础, 可望通过基因免疫获得免疫原性强、以低剂量即可有效刺激机体产生T细胞和B细胞应答、安全可靠的新型结核病疫苗.
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