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高压氧对一氧化碳中毒迟发性脑病防治的研究进展

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Author:: No author available

Journal Title:: Chinese Journal of Nautical Medicine and Hyperbaric Medicine

Issue:: 6

DOI:: 10.3760/cma.j.issn.1009-6906.2016.06.027

Key Word:: No keyword available

Abstract：一氧化碳(carbon monoxide,CO)是由碳及其化合物不完全燃烧形成的性质稳定且无色、无味的气体,它是造成中毒性死亡最常见的窒息性气体之一.CO中毒可引起机体多系统的损害,其中以大脑损害最为严重.若CO中毒患者即使经过治疗仍有10％～ 30％的患者会出现认知功能障碍、人格改变、大小便失禁、帕金森综合征、步态不稳及其他运动功能缺陷,个别患者也可出现抑郁、焦虑等精神症状[1],临床上把CO中毒患者昏迷后恢复至神志清醒状态2～60 d为假愈期,再次出现一系列以痴呆、精神症状和锥体外系为主的神经系统疾病称为一氧化碳中毒迟发性脑病(delayed encepholopthy after acute carbon monoxide poisoning,DEACMP).DEACMP不仅极大地影响患者的生活质量,也给社会和家庭带来巨大负担[2].

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