Abstract: Objective To study manipulating time and feasibility of simulated decompression craniectomy aboard ship under different sea status.Methods A hydraulic simulator was used to simulate the 4 different rolling and pitching states of the ship (i.e.A、B、C and D).Twenty hybrid dogs were randomly divided into groups for our present study.Simulated decompression craniectomy was performed to measure manipulating time and carry out feasibility study.Results Decompression craniectomy was completed successfully on experimental dogs without any death occurred following an observation of at least 48 hours.No differences in manipulating time could be noted(P>0.05).Conclusions Though manipulating accuracy aboard ship was affected to a certain degree,decompression craniectomy could be performed aboard ship under the four sea states.