Abstract： Objective To investigate hemodynamic effects of simulated violent rolling of naval vessels on lesion induced by seawater immersion combined with shock in anesthetized dogs. Methods Fourteen dogs were randomly divided into two groups: the immersion group and the control group, each consisting of 7 animals. In the immersion group, the animals were immersed in the seawater for 30 minutes, then taken out of the seawater. Heart rate (HR), central venous pressure (CVP), mean pulmonary arterial pressure (MPAP) were carefully monitored, following basal anesthesia and endotracheal intubation. Then, a model of hemorrhagic shock was developed by venetomy. Animals in the control group experienced violent roiling with a horizontal angle greater than 45 degrees and frequencies of 10～15 times per minute for a duration 20 minutes. The experimental group was immersed in the seawater with a temperature of about 20 ℃ and for a duration 30 minutes, then also experienced identical violent rolling as the control group for 20 minutes. Hemodynamic changes were recorded both before rolling and 1, 2, 4, 6, 10, 15, 20 minutes after rolling. Results Downward fluctuation of hemodynamic data could be induced by rollings, but returned to pro - rolling levels in 5～10 minutes. For animals in the control group, the extent of drop in blood pressure was higher when a comparison was made between the control and the immersion groups (P<0.05). Conclusions Violent rolling had certain effects on hemodynamic changes in anesthetized dogs combined with seawater immersion following anesthesia.