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Influences of different resclle environment on therapy effects of sea warfare injury

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Author:
No author available
Journal Title:
CHINESE JOURNAL OF NAUTICAL MEDICINE AND HYPERBARIC MEDICINE
Issue:
6
DOI:
10.3760/cma.j.issn.1009-6906.2008.06.006
Key Word:
海战伤;海上救治;实验研究;Sea warfare wound;Treatment at sea;Empirical study

Abstract: Objective To investigate effective methodes on sea warfare injury in different rescue environment. Methods After 60 dogs were subjected to craniocerebral firearm injury, open chest injury, open abdominal injury, limbs injury and burn injury, they were randomly divided into sea warfare wound group Ⅰand sea warfare wound group Ⅱ, land warfare wound group, with 20 dogs in each group. The laboratory rooms were founded at dock medical aid station in sea warfare wound group Ⅰ, in hospital ship and warship in sea warfare wound group Ⅱand at land medical aid station in land warfare wound group. The animals in two groups with sea warfare were immersed for 30 min in seawater after wound and received combined therapy, including in routine treatment and drug treatment, for example, 5% glucose liquid 500 ml, scopolamine 20 mg/8 h, dexamethasone 40 mg/8 h and vitamin B(6) 3 - 5 g/8 h. The dogs in land warfare group were not immersed and only received routine treatment. Temperature, plasma osmotic pressure and the changes of blood electrolytes had being detected for 24 h and wound infection rate and mortality in the three groups were compared in three days. Results The two groups with sea warfare wound had more severe traumatic condition than land warfare wound group. They appearanced hypothermia, high plasma osmotic pressure, hypernatrium, hyperchloraemia and metabolic acidosis. At 12 h after the dogs in the two groups with sea warfare wound were treated, all indexes in the dogs were recovered normal level. The wound infection rate was 15% in land warfare wound group, 40% in sea warfare wound group Ⅰand 50% in sea warfare wound group Ⅱin three days after wound. The mortality was 30% in land warfare wound group, 40% in sea warfare wound group Ⅰand 50% in sea warfare wound group Ⅱin three days after wound. The mortality and wound infection rate of animals were apparently higher in the sea warfare wound group Ⅱthan those in sea warfare wound group Ⅰand in land warfare wound group (P < 0.01). Conclusions After sea warfare wound, seawater immersion can severely influence on plasma osmotic pressure, electrolyte balance and hypothermia. It could be a chief reason of high mortality of experimental dogs that the sea environment could obviously influence on therapeutic effect of sea warfare wound. Early infusion of hypotonic solution could significantly reduce plasma osmotic pressure, retrieve electrolyte balance and increase survival rate.

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