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超选择性前列腺动脉栓塞术治疗良性前列腺增生的研究进展

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Author:: No author available

Journal Title:: Chinese Journal of Radiology

Issue:: 6

DOI:: 10.3760/cma.j.issn.1005-1201.2017.06.021

Key Word:: No keyword available

Abstract：良性前列腺增生(benign prostatic hyperplasia,BPH)是导致中老年男性排尿障碍的最常见疾病,主要发生于前列腺移行带.增生腺体凸向后尿道,使尿道伸长、弯曲、受压变窄,引起膀胱出口梗阻、排尿困难等下尿路阻塞症状(lower urinary tract symptoms,LUTS).50岁以上男性患病率超过50％,80岁以上达90％[1].严重者可导致尿潴留、反复血尿和尿路感染,甚至引起梗阻性肾功能衰竭,严重影响中老年男性的生活质量.BPH的传统治疗方法主要包括保守治疗(药物治疗及随访观察)、外科治疗和经皮穿刺微创治疗等,药物治疗适用于有中等程度症状的LUTS患者,但治疗费时较长、需要持续用药、有一定药物不良反应[2];外科治疗及经皮穿刺微创治疗也具有各自的局限性.超选择性前列腺动脉栓塞术(prostatic artery embolization,PAE)是一种较新的治疗方式,在欧洲已经作为无手术指征或手术高风险BPH患者可选择的方法,其优势在于创伤小、无需全身麻醉或腰麻、可重复治疗、不影响其他治疗、无传统治疗方法的不良反应和并发症(如术后出血、尿瘘、逆行射精等性功能异常问题)等.笔者对PAE的研究进展进行综述.

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