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基于体素内不相干运动的扩散加权成像在肾脏疾病中的应用进展

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Author:: No author available

Journal Title:: 中华放射学杂志

Issue:: 3

DOI:: 10.3760/cma.j.issn.1005-1201.2016.03.019

Key Word:: No keyword available

Abstract：传统DWI成像技术假设水分子在组织内的限制性扩散符合自由扩散特征，故可以采用单一b值进行DWI成像，得到的扩散系数是ADC值。但是，传统的DWI技术并未对组织内水分子的不同运输模式加以区分。体素内不相干运动（intravoxel incoherent motion，IVIM）弥补了传统DWI的不足[1]，可以更为准确地描述不同组织的特性，尤其在水分子动力学复杂的组织，IVIM较传统DWI的优势更为突出[2-6]。肾脏是重要的排泄器官，水、离子等不断在肾小管、间质及血管间转运，肾脏组织分子运动较为复杂。另外，肾脏血管容积分数为25%～40%，每分钟的肾血流量约相当于心输出量的1/4，是机体供血量最丰富的器官[7]，肾脏高血流灌注、高水分子代谢的特点使IVIM效应在肾脏尤为显著。笔者对IVIM的原理及在肾脏疾病中的应用进展进行综述。

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