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MRI findings and correlation with pathological features in breast phyllodes tumor

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Author:
No author available
Journal Title:
Chinese Journal of Radiology
Issue:
12
DOI:
10.3760/cma.j.issn.1005-1201.2011.12.007
Key Word:
乳腺肿瘤;磁共振成像;对比研究;Breast neoplasms;Magnetic resonance imaging;Comparative study

Abstract: Objective To study the MR Imaging features of breast phyllodes tumor (PT),and to correlate it with pathological results.Method Clinical and MRI findings were retrospectively reviewed in twenty-seven women with 28 PTs lesions confirmed by surgical pathology.Statistical analyses were one-way ANOVA for size analysis,Fisher exact test for analysis of MR appearances and Spearman correlation to study the relationship between MRI findings and BI-RADS categories.Results ( 1 ) The histologic findings were benign,borderline and malignant PTs in 14.3% (4/28),53.6% (15/28) and 32.1% (9/28) of lesions,respectively.(2) The mean maximum-diameter were (6.4 ± 3.9) cm,(5.7 ± 2.2) cm in borderline type and (4.8 ± 1.8)cm in benign type respectively.The results showed differences in lesion's size among the three type (F = 287.541,P =0.000),especially between malignant and benign type (P = 0.033 ).(3)Internal non-enhanced septations and silt-like changes on enhanced images,as well as time-signal curve on MRI correlated significantly with the histological grade ( P < 0.05 ).( 4 ) If the category BI-RADS ≥ 4a was considered to be a suspicious sign for malignant lesion,the diagnostic accuracy of MRI would be 96.4% (27/28),and the BI-RADS category of the MRI could reflect the PT's histological grade with a low correlation coefficient ( r = 0.382,P = 0.045 ).Conclusion The findings of PT on MRI have some characteristics,with tumor size and several MRI features correlating with the histological grade of breast PT.

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